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Real-time monitoring of vancomycin using a split-aptamer surface plasmon resonance biosensor
Published article Analyst 2025
3 days ago


Easy SPR experiment set-up: the Affinité sensor difference
One common SPR optical set-up widely used by most commercial SPR instruments involves a prism coupler. This component couples light to a...
Apr 2, 2024


Evaluation of a Novel Vaccine Platform by Using Portable SPR
This blog highlights the use of Affinité's P4SPR to evaluate the effectiveness of a unique vaccine platform in clinical samples.
Jan 18, 2022


Using Portable SPR to Speed Up Your Lateral Flow Assay Development
Conventional SPR has many advantages over ELISA when it comes to speeding up lateral flow assay development. Please read for more details.
Dec 20, 2021


Conventional SPR: Still the Best Choice for my Biosensing Needs
This blog highlights the key advantages of conventional SPR and outlines performance issues that are associated with localized SPR (LSPR).
Dec 18, 2021


Binding Interaction Studies Between Heparin and SARS-CoV-2 by Using P4SPRâ„¢
Summary of a research article that used P4SPR to do a competition assay between heparin and its derivatives and a SARS-CoV-2 protein.
Nov 12, 2021


Surface Plasmon Resonance for Protein-Protein Interactions
A general blog about SPR for protein-protein interactions and its advantages.
Nov 4, 2021


Afficoatâ„¢ for Reducing Non-Specific Adsorption in SPR Experiments
Comparison of surface chemistries between Afficoatâ„¢, other peptide sequences, PEG, and CM-Dextran. Examples of clinical samples used.
Sep 29, 2021


6 Advantages of Surface Plasmon Resonance Technology
What are the top advantages of using surface plasmon resonance? SPR is compared to other techniques such as ELISA and MST.
Sep 7, 2021


SPR to Examine Cross-Reactivity of Antibodies with Native and Variant SARS-CoV-2 Spike Proteins
Read about how Affinité's P4SPR™ advances COVID-19 research in terms of cross-reactivity of antibodies against spike protein variants.
Jul 30, 2021


SPR Platform Based on Ionic Liquids for the Detection of a Breast Cancer Biomarker in Cell Lysates
Read about how ionic liquids can be used to reduce non-specific adsorption for the detection of a breast cancer biomarker in cell lysates.
Jun 17, 2021


SPR for Enriching Synthetic Biology Research
Examples of how SPR can advance synthetic biology research. Demonstration of Affinité's P4SPR™ platform in this field.
May 25, 2021


Portable SPR for On-Site Testing of Environmental Contaminants
Summary of a paper that used the P4SPRâ„¢ to detect RDX in groundwater in the field during winter and summer seasons.
May 4, 2021


The Ability of SPR Compared to BLI to Detect Prostate-Specific Antigen in Human Serum
This blog summarizes a study that used 3D polyelectrolyte to detect PSA in clinical samples on Affinité's P4SPR™ platform instead of BLI.
Mar 15, 2021


Detection of Liposomes by Surface Plasmon Resonance
A proof-of-concept experiment demonstrating the use of Affinité's P4SPR™ to rapidly detect folate-modified liposomes and improve protocol.
Dec 31, 2020


Advantages of SPR over ELISA
Comparison of SPR and ELISA. Key features of SPR are highlighted as well as being able to detect low-affinity interactions.
Nov 13, 2020


Manual Injection vs Pump-Assisted SPR Experiment
A brief description of manual injection vs pump modes in surface plasmon resonance experiments. Factors to consider are also listed.
Nov 5, 2020


SPR Sensorgram Explained
Explanation of how a sensorgram is produced and its phases. Generating a sensorgram with the P4SPRâ„¢.
Oct 15, 2020


Rapid Quality Control of Antibodies Using P4SPRâ„¢
Here is a quick SPR experiment that can be done to check the quality of the same type of antibodies from different sources.
Sep 29, 2020


The Advantages of a Portable SPR Instrument
This blog lists the advantages of a portable SPR instrument vs a large SPR system. It highlights the key features of Affinité's P4SPR™.
Sep 16, 2020
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