Real-time SPR.
Redefined.

Over 100 peer-reviewed publications. Patented lensless technology. A complete ecosystem — instrument, microfluidics, consumables, software, and intelligence layer — built for every bench.

100+ peer-reviewed publications
15+ countries
10+ years of SPR innovation
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The platform
behind the science.

A complete SPR ecosystem built from the optics up — patented lensless architecture, integrated microfluidics, proprietary surface chemistry, and purpose-built software, all co-engineered to work as one. The platform extends beyond the bench: SPARQ™ (Surface Plasmon Analysis Result Quality) is embedded in the instrument — real-time diagnostics and method guidance on every run. Sparq Bio™ goes further as a connected AI platform, bringing cloud intelligence and cross-experiment learning to your lab. And Affibio delivers expert-run SPR directly to your program when you need results without the instrument.

5 injections. 15 minutes. From sample to binding insight.

The Platform

Six pillars.
One platform.

Every component — from optics to AI — built to work together. The only SPR system where the instrument, the fluidics, the chemistry, and the software were designed as one.

1Lensless SPR
2Full-Range Microfluidics
3Premium Consumables
4All-In-One Software
5SPARQ
6Sparq Bio
Core Technology

Lensless SPR


Patented. Core SPR instrument tech with none of the optics that make it large, costly and complicated. No one else has this architecture.

Proprietary
Fluidics

Full-Range Microfluidics


Microfluidics engineered from simple clog-free static to cutting-edge integrated flow controlprecision testing at every scale.

Static & Flow
Consumables

Premium Consumables


Disposable high-quality gold sensors with surface chemistry engineered to control non-specific binding — standard and proprietary options, validated reagents for every test.

Afficoat
Software

All-In-One Software


Affilabs — proprietary data processing engineered for high-quality sensorgrams. Guided workflows and instant outputs that make SPR accessible to any researcher.

Affilabs
In-Device Intelligence

SPARQ™


Embedded in the instrument. Real-time diagnostics, method guidance, and run quality monitoring — Surface Plasmon Analysis Result Quality built into every experiment, no cloud required.

SPARQ
Connected AI Platform

Sparq Bio™


Beyond the instrument. Sparq Bio extends SPARQ to the cloud — cross-experiment learning, AI-assisted method optimization, and lab-wide workflow integration. Coming soon.

Coming Soon

The Instruments

Same platform. Different workflows.

Two complementary ways to get answers fast — from rapid first-look binding to rigorous, publishable kinetics.

Portable Static SPR P4SPR 2.0
P4SPR 2.0 — Static SPR instrument

The ultra-compact static SPR for rapid scouting. Run yes/no binding checks, estimate concentrations in complex or crude media, and develop methods quickly — think label-free ELISA with real-time readout across up to 4 parallel channels. No microfluidics, no headaches, laptop-powered.

Use to de-risk experiments, scout buffers, and screen directly in serum or lysate before committing to flow.

Learn more →
Benchtop Flow SPR P4PRO
P4PRO with AffiPump — Flow SPR system

Full kinetic characterization with controlled association and dissociation. Precise kon, koff, and KD — cleaner baselines at low analyte concentrations, better limit of detection, and automated injections. Autosampler integration in development for higher throughput.

Move here when you need rigorous kinetics, publication-ready data, and the precision that flow-based SPR delivers.

Learn more →

Together, static and flow streamline the whole workflow — from first look to publishable kinetics — on compact systems that fit your bench and your budget.

Need a custom configuration? We do hardware and application customization — talk to us →

Software

AffiLabs.core —
built for your instrument.

Instrument control, data acquisition, and real-time analysis — all in one desktop application. Runs on Windows 10/11, connects via USB, and works with both the P4SPR and P4PRO.

Includes SPARQ — the smart operation support assistant built directly into the software. Step-by-step guidance, no ticket system, no wait.

Explore AffiLabs.core →

Control

Real-time instrument control & live sensorgram display

Analysis

Kinetic & steady-state fitting with one-click export

Quality

Signal quality scoring & leak detection per channel

SPARQ

Smart built-in support — answers without leaving the app

Affibio

Not ready to own an instrument?

SPR expertise delivered to your program — no instrument required. Expert-run experiments, validated methods, long-term scientific collaboration.

Learn more at affibioanalytics.com →

Where the platform goes

Drug Discovery

Lead optimization, target engagement, and fragment screening — real kinetics at every stage of your pipeline.

Antibody Development

Affinity ranking, epitope binning, biosimilar characterization — know exactly how your antibody binds before you scale.

Diagnostics & Biomarkers

Validate binding specificity and sensitivity early — before your diagnostic assay reaches clinical development.

Biosensor R&D

Aptamer selection, surface optimization, and detection limit validation — all in real time, on the same platform.

Environmental & Food Safety

Contaminant detection and field-deployable sensing — the portable form factor goes where the samples are.

Vaccines & Immunology

Antigen-antibody interactions, vaccine candidate evaluation — binding data that drives decisions at every checkpoint.

Knowledge Base

The science is on the shelf.

Application notes, protocols, guides, and 100+ peer-reviewed publications — everything you need to plan, run, and publish your SPR experiments.

Application Notes

Real experiments across drug discovery, antibody QC, environmental sensing, and more — see exactly how labs are putting the platform to work.

Guides & Protocols

From surface chemistry fundamentals to step-by-step immobilization protocols — written for reproducibility, from first experiment to publication.

Publications

100+ peer-reviewed papers from labs worldwide. Browse the body of work built with Affinité instruments — and find the citation you need.

Explore the Resource Hub →

Science happens here

Our community of researchers, in their labs, doing real work.

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P4PRO instrument in the lab
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Contact Us

Get in touch with us and we'll get back to you as soon as possible