Resources · Article · October 2025
A decade of portable SPR, a biopharma mAb case study, platform evolution, and what's coming next.
In 2015, we set out to build SPR instruments that researchers could actually afford, actually use, and actually trust. Ten years later, that mission hasn't changed — but the platform has grown significantly. From a single portable instrument to a complete ecosystem: the P4SPR, the P4PRO, integrated microfluidics, proprietary surface chemistry, and software built around the data.
A biopharma manufacturer needed quality monitoring during upstream antibody production — without disrupting the facility or waiting for core facility results. They deployed the P4SPR on-site and ran direct antibody analysis in 5-minute SPR runs. Over 20 process conditions. Under 2 hours. Results correlated directly with active molecular concentrations.
"Real-time production monitoring, directly in the facility. Five minutes per run. Over 20 conditions. Same day."
When we launched the P4SPR, we offered 4 surface chemistry options. Today we offer 20+ — expanded through strategic partnerships and proprietary development under the Afficoat line. The instrument portfolio grew from a single portable device to include the P4PRO for full kinetic characterization, AffiPump for precision flow control, and lensless SPR architecture that has now been patented.
The next phase is about flexibility. Mobile SPR services that bring the instrument directly to your facility — on-site, same-day data, no sample shipping. For labs that need SPR results without the instrument, Affibio delivers expert-run experiments and full characterization as a service.
