About Affinité Instruments

The barriers to SPR have never been scientific.

We built a company — and rebuilt a technology — on that premise.

The Origin

Born in a research lab. Built for every lab.

Surface plasmon resonance is the gold standard for measuring how molecules bind. The data it produces — binding kinetics, affinity constants, real-time interaction curves — underpins drug discovery, biologics development, and fundamental biochemistry across the life sciences. The market for SPR is large and growing. The problem is who can access it.

For decades, the instruments that dominated this space were designed for enterprise. They cost $300,000 or more. They required dedicated specialists, significant bench space, and institutional infrastructure. Good instruments — but built for the top 20% of labs with the budget to match.

The barriers were never scientific. SPR works. The barriers were cost, complexity, and access — the result of engineering and business decisions made a generation ago that locked most researchers out of data they legitimately need.

"We decided not to build a cheaper version of what already existed. We rebuilt the technology from the ground up."

Affinité Instruments grew out of Jean-François Masson's research group at the Université de Montréal, where years of work on SPR optics and plasmonic biosensors produced a fundamentally different approach to how an SPR instrument could be built. That research became the foundation of a company. Founded in 2015 and built entirely on non-dilutive funding, Affinité has taken that technology from a university prototype to instruments running in labs across 15+ countries.

The Journey

From lab bench to pharma — without losing the science.

We started as an academic spin-off. We are still scientists. What changed is who needs the data.

2015

Founded — the university spin-off

Incorporated out of Jean-François Masson's lab at the Université de Montréal. First customers: academic researchers who already knew the science and wanted an instrument they could actually afford. Early publications establish the platform's credibility in SPR methods, surface chemistry, and drug monitoring.

2017–19

First international traction

Instruments reach labs across North America and Europe. Publications span therapeutic drug monitoring — methotrexate, asparaginase — and clinical biosensing. The portable form factor starts proving its value beyond the university bench: researchers bring it to the sample, not the other way around.

2020

COVID-19 — field deployment at scale

The pandemic creates overnight demand for rapid, portable serology. Labs on four continents use the P4SPR for SARS-CoV-2 antibody detection, spike protein binding studies, and vaccine response monitoring. Eight publications in a single year. The instrument's portable, robust design proves indispensable in conditions where a $300K benchtop system was never going to go.

2021–23

Drug discovery and biomanufacturing enter the picture

Publication volume peaks. Application areas broaden well beyond academic biosensing: fragment screening and lead optimization in drug discovery programs, antibody QC and kinetics for biotech, AAV bioproduction monitoring for gene therapy, PD-L1 and cancer biomarker detection. The customer profile shifts. Small biotech and pharma R&D teams are running the same platform that started in university labs.

Today

A research standard — 15+ countries, 100+ publications

Instruments are running in academic labs, biotech startups, pharma R&D groups, and diagnostics companies across 15+ countries. Therapeutic drug monitoring, Alzheimer's research, biomanufacturing QC, environmental sensing — the platform goes where the science goes. We are still the same team. The science is still what drives everything.

The Team

Small team. Serious science.

The instruments are real. The publications are real. The customers are real. We are a small group of scientists, engineers, and commercial people who have spent years on this problem — and who still answer the phone when a researcher needs help with their experiment.

Ludovic Live
Ludovic Live Co-founder & CEO
Jean-François Masson
Jean-François Masson Co-founder · Sensor Director, Affinité Science
Joelle Pelletier
Joelle Pelletier Co-founder · Bioanalytics Director, Affinité Science
Shuo (Sandy) Zhao
Shuo (Sandy) Zhao Applications & Sales
Meet the full team →

See it in your lab.

A 30-minute demo is enough to understand why researchers in 15+ countries chose the platform. No commitment, no sales pitch — just the instrument and your questions.

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