Resources · Article · January 2026
A US patent, a precision kinetics case study, and the carry-on test — three things that happened this month.
The US Patent Office has granted Affinité Instruments a patent for our lensless SPR architecture — the core innovation that makes our instruments compact, affordable, and genuinely different from everything else on the market.
Traditional SPR systems rely on precise optical alignment — lenses, prisms, and complex mechanics that add size, cost, and fragility. Our architecture achieves the same measurement by eliminating the lens entirely. The result: a smaller instrument, a simpler workflow, and a path to miniaturization that conventional optics simply can't follow.
"Simplicity here isn't a compromise — it's a consequence of getting the physics right."
This patent protects the foundation of everything we build — and sets the stage for the next generation of instruments that will extend lensless SPR to workflows that have never been accessible before.
We ran a Protein A–IgG binding assay on the P4PRO to show what flow-controlled SPR delivers when everything is dialled in. AffiCoat sensors with reference channels. AffiPump fluidics for stable, reproducible flow. Kinetics fitting that matches published literature values — with better curve quality than expected.
"Kinetic constants matching literature values — with superior data fitting. Achievable results, directly on your bench, in under two hours."
The full application note walks through the surface preparation, injection protocol, and fitting approach — with all raw data and parameters included.
We packed a P4PRO into a carry-on. Checked it in, flew across the Atlantic, unpacked it at the destination. Powered it on. Ran a binding assay.
It worked. Flawlessly.
"Powerful SPR can also be compact, robust, and deliver high-quality kinetic data directly to your bench — wherever that bench happens to be."
The P4PRO fits in a carry-on. Our service model fits your schedule. Whether you're running experiments in your home lab or setting up at a collaborator's site — the instrument travels with you, and it's ready when you are.